OSMT (Ontario Society of Medical Technologists) Practice Exam

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An IgM molecule:

can cross the placenta
is the largest antibody
is a monomer
cannot fix complement

The correct answer is: is the largest antibody

An IgM molecule is the largest antibody among all the antibody classes. It is a pentamer, made up of five monomeric units joined together by a protein structure called the J-chain. The size and structure of IgM allow it to have a high avidity for antigens, making it effective in agglutination and neutralization of pathogens.