OSMT (Ontario Society of Medical Technologists) Practice Exam

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What is required for the safe dissolution of a Nucleopore filter?

a. saline
b. alcohol
c. Isotones
d. none of the above

The correct answer is: b. alcohol

The correct choice is alcohol because Nucleopore filters, which are made of polycarbonate or other thermoplastic materials, can be effectively dissolved in certain organic solvents, particularly alcohols. When using alcohol for this purpose, the solvent interacts with the filter material, breaking down its structure without leaving behind significant residues that could contaminate any subsequent analyses. Saline, on the other hand, is an aqueous solution and is not effective for dissolving such materials. Isotonic solutions typically maintain osmotic balance but do not have the chemical properties necessary for dissolving Nucleopore filters. Lastly, stating that none of the above would imply that no solvent is needed, which is inaccurate in this context as a solvent is indeed required for proper dissolution.