OSMT (Ontario Society of Medical Technologists) Practice Exam

Which cell is responsible for releasing histamine?

1. a. B cell

2. b. T cell

3. c. mast cell

4. d. macrophage

The correct answer is: c. mast cell

The correct choice is indeed the mast cell. Mast cells play a critical role in the immune system, particularly in allergic reactions and inflammation. They are located in connective tissues and are integral for the body's defense mechanisms. When triggered by allergens or certain pathogens, mast cells degranulate, releasing histamine and other mediators that contribute to increased blood flow and the symptoms associated with allergic responses, such as swelling and redness. In contrast, B cells are primarily responsible for the production of antibodies, while T cells are involved in cell-mediated immunity and the direct killing of infected or cancerous cells. Macrophages are important phagocytic cells that engulf and digest pathogens and debris, but they do not play a direct role in the release of histamine. Hence, while each of these cell types has specific functions within the immune system, mast cells are uniquely known for their role in histamine release.